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  2. Ivabradine - Wikipedia

    en.wikipedia.org/wiki/Ivabradine

    Ivabradine, sold under the brand name Procoralan among others, is a medication, which is a pacemaker current (I f) inhibitor, used for the symptomatic management of heart-related chest pain and heart failure. Patients who qualify for use of ivabradine for coronary heart failure are patients who have symptomatic heart failure, with reduced ...

  3. Cardiovascular agents - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_agents

    Non-dihydropyridines are contraindicated in patients with heart failure with reduced ejection fraction (HFrEF), and second- or third-degree atrioventricular block. [13] Special attention should be given to the coadministration of non-DHP with beta-blockers or ivabradine due to the increased risk of bradycardia. [13]

  4. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    [10] [11] [18] To investigate its use for heart failure in those with a preserved LVEF (HFpEF), Novartis funded the PARAGON-HF trial which was designed to investigate the use of sacubitril/valsartan in the treatment of HFpEF patients with a LVEF of 45% or more. Concluding in 2019, it failed to show significance for reducing hospitalisation ...

  5. Roberto Ferrari (cardiologist) - Wikipedia

    en.wikipedia.org/wiki/Roberto_Ferrari_(cardiologist)

    SHIFT (Systolic Heart failure treatment with the IF inhibitor ivabradine Trial) showed the benefits of ivabradine in heart failure patients and allowed the registration at EMA and FDA of perindopril in heart failure patients with heart rate > 70 b/min and its indication in the American and European guidelines. [75] [76] [77] [78]

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    Think about the healthy life years you gain just from minimizing these risks, considering lung cancer and heart disease are by far the leading causes of premature deaths among men and women in the US.

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    A woman who was brutally murdered in Queens more than three decades ago has finally been identified - through advanced DNA testing - as a mom who went missing soon after celebrating her daughter's ...

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