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With this revelation, a judge ordered a new round of DNA testing in Alexander's case. Hairs found at the scene of the rape were submitted to mitochondrial DNA testing. [4] At the time of Alexander's original conviction, such testing was not available in the state of Indiana. The tests proved that the DNA did not match Alexander's profile, but ...
Blake is a world-renowned forensic scientist who pioneered the establishment of PCR testing as a reliable forensic science. The prosecution had tried to retain Blake before learning the defense had already done so. All of the DNA experts were familiar with Blake and Gary Sims, who ran the state department lab, was one of his students. [64]
The Jackson County Sheriff's Office, in cooperation with the Mississippi State Crime Lab, reached out to Othram to use advanced DNA testing to identify the victim. On September 21, 2021, it was announced that she had been identified as 44-year-old Clara Birdlong from Leflore County, Mississippi .
Developed in 1991, [10] DQ alpha testing was the first forensic DNA technique that utilized the polymerase chain reaction. [11] This technique allowed for the use of far fewer cells than RFLP analysis making it more useful for crime scenes that did not have the large amounts of DNA material that was previously required. [ 12 ]
Mitochondrial DNA is a small portion of the DNA contained in a eukaryotic cell; most of the DNA is in the cell nucleus, and, in plants and algae, the DNA also is found in plastids, such as chloroplasts. [3] Human mitochondrial DNA was the first significant part of the human genome to be sequenced. [4]
The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA).
The MT-ND4 gene is located in human mitochondrial DNA from base pair 10,760 to 12,137. [5] [11] The MT-ND4 gene produces a 52 kDa protein composed of 459 amino acids.[12] [13] MT-ND4 is one of seven mitochondrial genes encoding subunits of the enzyme NADH dehydrogenase (ubiquinone), together with MT-ND1, MT-ND2, MT-ND3, MT-ND4L, MT-ND5, and MT-ND6.
In human mitochondrial genetics, Haplogroup K1a1b1a is a human mitochondrial DNA (mtDNA) haplogroup. The K1a1b1a mitochondrial DNA haplogroup subclade is found in Ashkenazi Jews and other populations. It is a subclade under haplogroup U'K.