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Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8] It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them. [7] [9] Side effects include rash and irritation where it is applied. [8]
Insecticides used for the treatment of head lice include lindane, malathion, carbaryl, pyrethrum, piperonyl butoxide, permethrin, phenothrin, bioallethrin, and spinosad. Many of the pediculicides in the market are either not fully effective or are ineffective when they are used according to the instructions.
Permethrin exerts its therapeutic effect by disrupting sodium transport across neuronal membranes in arthropods, inducing depolarization. This mechanism ultimately leads to respiratory paralysis in the affected arthropod, establishing permethrin as a potent agent in managing scabies and pediculosis.
Treatment: Permethrin is the drug of choice for the treatment of scabies, per the CDC. Topical permethrin should be applied every two to three days for up to two weeks.
At first, treatment is usually with topical permethrin 1% cream, which can be bought over the counter without a prescription. It is applied to the areas affected by pubic lice and washed off after 10 minutes. [6] Brands of permethrin include 'Lyclear', available in the UK as a creme rinse or dermal cream at 5% strengths.
Use a retinol cream. Retinol increases cell turnover, which can lighten pigmentation. "For melasma, retinol can be used as a stand-alone topical and is also commonly prescribed as a combination ...
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