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Ascorbate peroxidase (or L-ascorbate peroxidase, APX or APEX) (EC 1.11.1.11) is an enzyme that catalyzes the chemical reaction. L-ascorbate + H 2 O 2 dehydroascorbate + 2 H 2 O. It is a member of the family of heme-containing peroxidases.
The following is a list of phosphodiesterase inhibitors. List. Adibendan; Aminophylline; Aminophylline dihydrate; ... This list was created from the NCI Thesaurus
Peroxidase can be used for treatment of industrial waste waters. For example, phenols, which are important pollutants, can be removed by enzyme-catalyzed polymerization using horseradish peroxidase. Thus phenols are oxidized to phenoxy radicals, which participate in reactions where polymers and oligomers are produced that are less toxic than ...
Class I, the intracellular peroxidases, includes: cytochrome c peroxidase (CCP), a soluble protein found in the mitochondrial electron transport chain, where it probably protects against toxic peroxides; ascorbate peroxidase (AP), the main enzyme responsible for hydrogen peroxide removal in chloroplasts and cytosol of higher plants; [4] and ...
In enzymology, a L-ascorbate oxidase (EC 1.10.3.3) is an enzyme that catalyzes the chemical reaction 2 L-ascorbate + O 2 ⇌ {\displaystyle \rightleftharpoons } 2 dehydroascorbate + 2 H 2 O Thus, the two substrates of this enzyme are L- ascorbate and O 2 , whereas its two products are dehydroascorbate and H 2 O .
An enzyme inhibitor stops ("inhibits") this process, either by binding to the enzyme's active site (thus preventing the substrate itself from binding) or by binding to another site on the enzyme such that the enzyme's catalysis of the reaction is blocked. Enzyme inhibitors may bind reversibly or irreversibly.
Phosphodiesterase-5. A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s).
It can be used to characterise enzyme kinetics, [49] to guide enzyme inhibitor development, [50] study ligand and metal binding [51] as well as analyse protein conformational change. [52] Assays using spectrophotometry were also used, [ 53 ] for example those that measure 2OG oxidation, [ 54 ] co-product succinate formation [ 55 ] or product ...