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Fluorouracil has been given systemically for anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers (especially head and neck cancers). [12] It has also been given topically (on the skin) for actinic keratoses, skin cancers and Bowen's disease [12] (a type of cutaneous squamous-cell carcinoma), and as eye drops for treatment of ocular surface squamous neoplasia. [13]
Myelosuppression, pulmonary toxicity, hepatotoxicity, neurotoxicity (high dose or intrathecal administration), anaphylactic reactions (rare), Stevens–Johnson syndrome (rare), Toxic Epidermal Necrolysis (rare), kidney failure (rare), osteoporosis (rare), skin and bone necrosis (rare) and macrocytic anaemia (rare).
Topical 5-fluorouracil (5-FU, Efudex, Carac) has been shown to be an effective therapy for diffuse, but minor actinic cheilitis. 5-fluorouracil works by blocking DNA synthesis. Cells that are rapidly growing need more DNA, so they accumulate more 5-fluorouracil, resulting in their death. Normal skin is much less affected.
This page was last edited on 28 April 2005, at 06:27 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
Hypochlorous acid’s ability to kill harmful bacteria while keeping the skin barrier intact makes it a versatile and gentle option for a wide range of skin concerns, says Carmen Castilla, M.D.
A plantar wart is a wart occurring on the bottom of the foot or toes. [5] Its color is typically similar to that of the skin. [2] Small black dots often occur on the surface. [5] One or more may occur in an area. [2] They may result in pain with pressure such that walking is difficult. [2] They are caused by the human papillomavirus (HPV). [2]
A seasonal greeting card, whether handwritten on personalized Christmas stationary or typed out on a tasteful e-card, is one way to show family and friends you care about them this holiday season ...
Perfect for those who want natural-looking, medium coverage that evens skin tone and covers redness, dark spots and imperfections, Estée Lauder's Futurist formula is a great all-season foundation ...
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