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  2. Protein-bound paclitaxel - Wikipedia

    en.wikipedia.org/wiki/Protein-bound_paclitaxel

    It is manufactured and sold in the United States by Celgene under the trade name Abraxane where it is designated as an orphan drug as first-line treatment, in combination with gemcitabine, for the orphan disease "metastatic adenocarcinoma of the pancreas".

  3. Analyses of MPACT Trial Evaluating ABRAXANE® Combination ...

    www.aol.com/2013/06/03/analyses-of-mpact-trial...

    The most common grade 3 or 4 adverse events in MPACT for ABRAXANE plus gemcitabine versus gemcitabine alone were neutropenia (38% vs. 27%, respectively), fatigue (17% vs. 7%) and peripheral ...

  4. Gemcitabine - Wikipedia

    en.wikipedia.org/wiki/Gemcitabine

    Gemcitabine, sold under the brand name Gemzar, among others, [1] is a chemotherapy medication used to treat cancers. [2] It is used to treat testicular cancer , [ 3 ] breast cancer , ovarian cancer , non-small cell lung cancer , pancreatic cancer , and bladder cancer .

  5. Celgene at ASCO: Ho-Hum, Ho-Hum, and Hmmm - AOL

    www.aol.com/2013/06/04/celgene-at-asco-ho-hum-ho...

    Ho-hum for AbraxaneFindings from a phase 3 study of Abraxane. Celgene was one of several companies presenting at the American Society of Clinical Oncology, or ASCO, annual meeting in Chicago this ...

  6. ABRAXANE® Plus Gemcitabine Demonstrates Significant Survival ...

    www.aol.com/news/2013-01-22-abraxane-plus...

    In the MPACT (Metastatic Pancreatic Adenocarcinoma Clinical Trial) study, ABRAXANE plus gemcitabine demonstrated a 59% increase in one-year survival (35% vs. 22%, p=0.0002) and demonstrated double ...

  7. Patrick Soon-Shiong - Wikipedia

    en.wikipedia.org/wiki/Patrick_Soon-Shiong

    He is the inventor of the drug Abraxane, which is used for lung, breast, and pancreatic cancer. Soon-Shiong is the founder of NantWorks, a network of healthcare, biotech, and artificial intelligence startups; [ 2 ] an adjunct professor of surgery and executive director of the Wireless Health Institute at the University of California, Los ...

  8. Celgene Corporation: Fast Growing Drugs About to Become ... - AOL

    www.aol.com/2014/02/05/celgene-corp-fast-growing...

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  9. FOLFIRINOX - Wikipedia

    en.wikipedia.org/wiki/FOLFIRINOX

    In the United Kingdom, the National Institute for Health and Care Excellence (NICE), in a draft guidance issued in 2014, rejected the use of Abraxane in treatment due to concerns of side effects, efficacy, and cost relative to Gemzar (gemcitabine). [10] However, on 18 May 2017 NICE issued a reappraisal for the use of Abraxane in the UK.