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Insulin lispro, sold under the brand name Humalog among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [5] It is delivered subcutaneously either by injection or from an insulin pump .
The company's primary revenue drivers are the diabetes drugs Humalog (insulin lispro) (1996) and Trulicity (dulaglutide) (2014). [12] Lilly was the first company to mass-produce both the polio vaccine, developed in 1955 by Jonas Salk, and insulin.
Eli Lilly and Company developed and marketed the first rapid-acting insulin analogue (insulin lispro rDNA) Humalog. It was engineered through recombinant DNA technology so that the penultimate lysine and proline residues on the C-terminal end of the B-chain were reversed.
(Reuters) -Eli Lilly has sent cease-and-desist letters to U.S. healthcare providers in recent days to stop the promotion of the compounded versions of its drugs for weight loss and diabetes, as ...
1983 Eli Lilly and Company produces biosynthetic human insulin with recombinant DNA technology, Humulin; 1985 Axel Ullrich sequences a human cell membrane insulin receptor. 1988 Novo Nordisk produces recombinant biosynthetic human insulin; 1996 Lilly Humalog "lispro" insulin analogue approved.
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Company Sales (USD millions/year) ∆ vs 2014 1 Adalimumab: Humira ... Humalog: Insulin lispro: 304,866: 6.15%: Eli Lilly and Company: Diabetes mellitus type 1 and 2 ...
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