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Sequencing of the agouti signalling peptide in the agouti gene coding region revealed a 2-base pair deletion in black domestic cats. These variants were absent in melanistic individuals of Geoffroy's cat , oncilla , pampas cat and Asian golden cat , suggesting that melanism arose independently at least four times in the cat family.
Leucism (/ ˈ l uː s ɪ z əm,-k ɪ z-/) [2] [3] [4] is a wide variety of conditions that result in partial loss of pigmentation in an animal—causing white, pale, or patchy coloration of the skin, hair, feathers, scales, or cuticles, but not the eyes. [4] It is occasionally spelled leukism.
A mutation in the protein coding region (red) can result in a change in the amino acid sequence. Mutations in other areas of the gene can have diverse effects. Changes within regulatory sequences (yellow and blue) can effect transcriptional and translational regulation of gene expression.
In the theory, mutation was the source of novelty, creating new forms and new species, potentially instantaneously, [1] in sudden jumps. [2] This was envisaged as driving evolution, which was thought to be limited by the supply of mutations.
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A mutation accumulation (MA) experiment is a genetic experiment in which isolated and inbred lines of organisms (so-called MA lines) are maintained such that the effect of natural selection is minimized, with the aim of quantitatively estimating the rates at which spontaneous mutations (mutations not caused by exogenous mutagens) occur in the studied organism.
Today's NYT Connections puzzle for Wednesday, January 15, 2025The New York Times
Another resident, Edvard Jensen, was more dismissive, telling DR that he didn’t believe Trump would invade Greenland. “He just wants the attention, and now he has it.”