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Uremic pruritus is caused by chronic kidney failure and is the most common internal systemic cause of itching. [2]: 52–3 Nalfurafine, an orally administered, centrally acting κ-opioid receptor agonist, is approved to treat the condition in Japan. [3]
Uremic frost is a colloquial description for crystallized urea deposits that can be found on the skin of those affected by chronic kidney disease (CKD). [1] Uremic frost was first described in 1865 by Harald Hirschsprung (1830-1916), a Danish pediatrician. He was also the first to describe Hirschsprung's disease in 1886. The disease now carries ...
Without intervention via dialysis or kidney transplant, uremia due to renal failure will progress and cause stupor, coma, and death. [2] Because uremia is mostly a consequence of kidney failure, its signs and symptoms often occur concomitantly with other signs and symptoms of kidney failure. [citation needed]
AKI - the other main type of kidney disease - can be caused by dehydration, blood loss, urinary tract obstructions such as kidney stones or blood clots, low blood pressure, or heart disease. It ...
The cause of chronic kidney disease is in some cases not known; it is referred to as chronic kidney disease of unknown aetiology (CKDu). As of 2020 [update] a rapidly progressive chronic kidney disease, unexplained by diabetes and hypertension, had increased dramatically in prevalence over a few decades in several regions in Central America and ...
Chronic kidney disease. Damage to nerves in the hands and feet (peripheral neuropathy) Stroke. Eye disease that may lead to blindness. Hearing loss. Gum disease. Skin issues, such as itching or ...
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