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The label will advise the appropriate dilution ratio, commonly 1:1000 or 1:100. Equipment to be sanitized should be thoroughly clean and left in contact with the solution for at least 2 minutes. Diluted iodophor is used extensively in the dairy industry for disinfecting milking parlors , particularly in the United Kingdom .
The Rideal–Walker coefficient, now only of historical interest, [1] is a figure expressing the disinfecting power of any disinfectant. It is the ratio of the dilution of the disinfectant that kills a microorganism to the dilution of phenol that kills the organism in the same time under identical conditions.
To calculate phenol coefficient, the concentration of phenol at which the compound kills the test organism in 10 minutes, but not in 5 minutes, is divided by the concentration of the test compound that kills the organism under the same conditions (or, probably more common, dividing the dilution factor at which the tested substance shows ...
The World Health Organization (WHO) recommend a 1:100 dilution of 5% sodium hypochlorite bleach solution for general disinfection, which yields 0.05% or 50 ppm of the active ingredient which requires a soaking time of 30 minutes or at least 10 minutes wet time if sprayed onto a nonporous surface. Specific studies on SARS-CoV-2 found that a ...
1:4 dilution is used for wound management applications; this contains 0.25% (w/v) available chlorine and has a pH of 10.5–11.2. [ 1 ] [ 2 ] The fluid has been used in endodontics , for example to irrigate an infected root canal , although it is not medically licensed for use in the mouth.
It is the concentration recommended by the U.S. Centers for Disease Control (CDC) as a household disinfectant. [19] In one study, bactericidal effects of sodium hypochlorite solution were observed at concentrations as low as 0.025%, without any tissue toxicity in vivo or in vitro.
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