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The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. [3] The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memory, language comprehension, and emotion association. [4]: 21 Temporal refers to the head's temples.
Studies have shown that activity in the medial temporal lobe (MTL) structures: [5] perirhinal cortex, parahippocampal cortex and the hippocampus are vital to the recollection of personal-event memories [6] along with other memories. the medial temporal lobe structures, parietal and frontal lobes of the brain, all contribute to forming and retrieving memories.
After Molaison underwent a bilateral medial temporal lobe resection to alleviate epileptic symptoms the patient began to suffer from memory impairments. Molaison lost the ability to encode and consolidate newly learned information leading researchers to conclude the medial temporal lobe (MTL) was an important structure involved in this process. [6]
The pathophysiology of anterograde amnesic syndromes varies with the extent of damage and the regions of the brain that were damaged. The most well-described regions indicated in this disorder are the medial temporal lobe (MTL), basal forebrain, and fornix. Beyond the details described below, the precise process of how we remember – on a ...
The hippocampus is located in the medial temporal lobe (subcortical), and is an infolding of the medial temporal cortex. [1] The hippocampus plays an important role in the transfer of information from short-term memory to long-term memory during encoding and retrieval stages. These stages do not need to occur successively, but are, as studies ...
Consolidation of STM into LTM at the molecular level presumably involves two processes: synaptic consolidation and system consolidation. The former involves a protein synthesis process in the medial temporal lobe (MTL), whereas the latter transforms the MTL-dependent memory into an MTL-independent memory over months to years (Ledoux 2007).
The perirhinal cortex is a cortical region in the medial temporal lobe that is made up of Brodmann areas 35 and 36.It receives highly processed sensory information from all sensory regions, and is generally accepted to be an important region for memory.
The medial temporal lobe is critical for successful destination memory because it is this region of the brain that controls our episodic memory, which includes destination memory. [2] The neurological processes responsible for destination memory are impaired by normal aging and are significantly affected by Alzheimer's disease.