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Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. [2] It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats.
Lufenuron is a veterinary preparation (known as Program) that attacks the larval flea's ability to produce chitin, necessary for the adult's hard exoskeleton, but it does not kill fleas. Flea medicines need to be used with care because many of them also affect mammals. Pyrethrin based flea treatments meant for dogs can be hazardous to cats.
It is also indicated for the treatment and control of intestinal roundworms (Toxocara canis and Toxascaris leonina), hookworms (Ancylostoma caninum and Uncinaria stenocephala), and whipworms (Trichuris vulpis).
It is effective against fleas, ticks, chewing lice and mosquitoes. [1] The active ingredients are imidacloprid, permethrin, and pyriproxyfen. This product is toxic to cats, [2] and it is not recommended to use it on dogs which share an environment with cats. [1]
The most infamous flea-to-human transmitted disease is the bubonic plague, which was caused by the bacterium Yersinia pestis.
As of 2017, there does not appear to be significant resistance among fleas to fipronil. [5] Fipronil is used as the active ingredient in flea control products for pets and home roach baits as well as field pest control for corn, golf courses, and commercial turf. Its widespread use makes its specific effects the subject of considerable attention.
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