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Autoimmune inner ear disease (AIED) was first defined by Dr. Brian McCabe in a landmark paper describing an autoimmune loss of hearing. [2] The disease results in progressive sensorineural hearing loss (SNHL) that acts bilaterally and asymmetrically, and sometimes affects an individual's vestibular system .
It is currently thought that Cogan syndrome is an autoimmune disease. The inflammation in the eye and ear are due to the patient's own immune system producing antibodies that attack the inner ear and eye tissue. Autoantibodies can be demonstrated in the blood of some patients, and these antibodies have been shown to attack inner ear tissue in ...
Autoimmune disease Primary organ/body part affected Autoantibodies Acceptance as an autoimmune disease Prevalence rate (US) Cit. Autoimmune retinopathy: Retina: Various Confirmed [97] Autoimmune uveitis: Uvea: Various Confirmed [98] Cogan syndrome: Inner ear and eye None specific Probable [99] Graves' ophthalmopathy: Eye muscles and connective ...
Known causes of sudden changes in hearing can include ear diseases, such as Meniere's disease, vestibular schwannoma (aka, a benign growth on the hearing nerve), or an autoimmune inner ear disease ...
Currently, it is estimated that this inner ear disease affects approximately 73 of 100,000 people in the United States – about 600,000 people ... Symptoms of Ménière's disease.
Cochlear hydrops preferentially affects the apex of the cochlea where low-frequency sounds are interpreted. Due to the fluid imbalance in this area, parts of the cochlea are stretched or under more tension than usual, which can lead to distortions of sound, changes in pitch perception, or hearing loss, all usually in the low frequencies.
Since the inner ear is not directly accessible to instruments, identification is by patient report of the symptoms and audiometric testing. Of those who present to their doctor with sensorineural hearing loss, 90% report having diminished hearing, 57% report having a plugged feeling in ear, and 49% report having ringing in ear ().
“When systemic and chronic inflammation accompanies these underlying diseases, it can affect multiple organ systems, manifesting as fatigue, muscle weakness, digestive disturbances, joint pain ...
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