Search results
Results from the WOW.Com Content Network
Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
Phytotoxicity describes any adverse effects on plant growth, physiology, or metabolism caused by a chemical substance, such as high levels of fertilizers, herbicides, heavy metals, or nanoparticles. [1] General phytotoxic effects include altered plant metabolism, growth inhibition, or plant death. [2]
SB-334867 is an orexin antagonist.It was the first non-peptide antagonist developed that is selective for the orexin receptor subtype OX 1, with around 50x selectivity for OX 1 over OX 2 receptors. [1]
High plasma triglycerides (from a high fat diet) and low blood sugar (hypoglycemia) increases orexin levels, which increases appetite through orexin-stimulated neuropeptide Y action. [1] A high fat diet more than a high calorie diet has been shown to increase obesity and orexin release.
In molecular biology, a reporter gene (often simply reporter) is a gene that researchers attach to a regulatory sequence of another gene of interest in bacteria, cell culture, animals or plants. Such genes are called reporters because the characteristics they confer on organisms expressing them are easily identified and measured, or because ...
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Both orexin receptors exhibit a similar pharmacology – the 2 orexin peptides, orexin-A and orexin-B, bind to both receptors and, in each case, agonist binding results in an increase in intracellular calcium levels. However, orexin-B shows a 5- to 10-fold selectivity for orexin receptor type 2, whilst orexin-A is equipotent at both receptors ...
In the field, plants in full sunlight, and not under canopy, or partly cloudy conditions, are considered to be at steady state. In this test, light irradiation levels and leaf temperature must be controlled or measured, because while the Y(II) parameter levels vary with most types of plant stress, it also varies with light level and temperature.