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The liquid version of NyQuil Cold/Flu Multi-symptom Relief, available in syrup and LiquidCap form. The recommended adult dose contains: Acetaminophen (650 mg/30 mL) (pain reliever/fever reducer) Dextromethorphan (30 mg/30 mL) (cough suppressant) Doxylamine succinate (12.5 mg/30 mL) (antihistamine/hypnotic) Alcohol (10% by volume)
Some states have restricted the sale of dextromethorphan to adults or put other restrictions on its purchase in place, similar to those for pseudoephedrine. As of January 1, 2012, dextromethorphan is prohibited for sale to minors in the State of California and in the State of Oregon as of January 1, 2018, except with a doctor's prescription. [50]
Each formulation also varies per dose. When purchasing over-the-counter medications, avoid purchasing multiple products with acetaminophen ingredients. The suggested maximum daily intake of acetaminophen is limited to <4 grams (4,000 mg) daily in adults or <2.6g (2,600 mg) daily in children <12 years of age to reduce the risk of liver damage.
In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users. A single case study suggests that the antidote to dextromethorphan overdose is naloxone, administered intravenously. [17]
The provider of a dextromethorphan containing product must acquire proof of age if they believe that the potential purchaser is below the age of 18. Any person found to possess more than one gram of pure dextromethorphan without the required credentials is subject to a $1000 fine for the first offense and a $2500 fine for each subsequent offense.
Mr. Carleton and Mr. Hovey, using Father John as the spokesman, began to manufacture and mass-produce the medicine in Lowell, until the company was sold and moved to Cody, Wyoming in the early 1980s. [2] Today, as sold, the active ingredient in Father John's Medicine is dextromethorphan hydrobromide.
Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (an antihistamine). [1] Introduced by Schering-Plough in 1949 as one of the first antihistamines, it is now owned by Bayer.
Dextromethorphan syrup Lean or purple drank (known by numerous local and street names ) is a polysubstance drink used as a recreational drug . It is prepared by mixing prescription-grade cough or cold syrup containing an opioid drug and an anti-histamine drug with a soft drink and sometimes hard candy .
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