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  2. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    All of these drugs inhibit the gastric H,K-ATPase by covalent binding, so the duration of their effect is longer than expected from their levels in the blood. [ 76 ] Targeting the terminal step in acid production, as well as the irreversible nature of the inhibition, results in a class of medications that are significantly more effective than H ...

  3. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.

  4. Antacid - Wikipedia

    en.wikipedia.org/wiki/Antacid

    An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion, or an upset stomach. [1] Some antacids have been used in the treatment of constipation and diarrhea. [2] Marketed antacids contain salts of aluminum, calcium, magnesium, or sodium. [2]

  5. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.

  6. Bismuth subsalicylate - Wikipedia

    en.wikipedia.org/wiki/Bismuth_subsalicylate

    Bismuth subsalicylate, sold generically as pink bismuth and under brand names including Pepto-Bismol, Pepti-Calm and BisBacter, is a medication used to treat temporary discomfort of the stomach and gastrointestinal tract. This includes an upset stomach, heartburn or other similar symptoms.

  7. Omeprazole - Wikipedia

    en.wikipedia.org/wiki/Omeprazole

    The drug binds non-competitively so it has a dose-dependent effect. [53] The inhibitory effect of omeprazole occurs within 1 hour after oral administration. The maximum effect occurs within 2 hours. The duration of inhibition is up to 72 hours. When omeprazole is stopped, baseline stomach acid secretory activity returns after 3 to 5 days.

  8. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Like other medications for the treatment of (ED), Cialis — and its generic version, tadalafil — can cause adverse effects at first. ... an upset stomach, or other digestive issues after taking ...

  9. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]

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