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Benzylamine, also known as phenylmethylamine, is an organic chemical compound with the condensed structural formula C 6 H 5 CH 2 NH 2 (sometimes abbreviated as PhCH 2 NH 2 or BnNH 2). It consists of a benzyl group, C 6 H 5 CH 2, attached to an amine functional group , NH 2 .
N,N-Dimethylbenzylamine can be synthesized by the Eschweiler–Clarke reaction of benzylamine [2] [3] Reactions
Benzyl is most commonly abbreviated Bn. For example, benzyl alcohol can be represented as BnOH. Less common abbreviations are Bzl and Bz, the latter of which is ambiguous as it is also the standard abbreviation for the benzoyl group C 6 H 5 C(O)−.
N-isopropylbenzylamine is a compound that has appeared in chemical literature often playing an intermediary role in applications of experimental synthesis and novel organic transformations.
acylation of a benzylamine with acetyl chloride (acetic anhydride is an alternative) In the Fischer peptide synthesis (Emil Fischer, 1903), [6] an α-chloro acid chloride is condensed with the ester of an amino acid. The ester is then hydrolyzed and the acid converted to the acid chloride, enabling the extension of the peptide chain by another ...
He discovered that heating benzaldehyde with formamide does not produce benzylidenediformamide as anticipated, but benzylamine. [2] In 1891, a colleague of Leuckart at the University of Göttingen, Otto Wallach, performed further reactions using alicyclic and terpenoid ketones as well as aldehydes, demonstrating the general application. [2]
Butenafine, sold under the brand names Lotrimin Ultra, Mentax, and Butop (In India only), is a synthetic benzylamine derived antifungal drug. It is structurally related to the allylamine antifungals terbinafine & naftifine.
Amine oxidase (copper-containing) (AOC) (EC 1.4.3.21 and EC 1.4.3.22; formerly EC 1.4.3.6) is a family of amine oxidase enzymes which includes both primary-amine oxidase and diamine oxidase; these enzymes catalyze the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines.