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  2. Replication crisis - Wikipedia

    en.wikipedia.org/wiki/Replication_crisis

    [h] The authors conclude that if replication is defined by a subsequent study finding a sufficiently similar effect size to the original, replication success is not likely even if replications have very large sample sizes. Importantly, this occurs even if replications are direct or exact since heterogeneity nonetheless remains relatively high ...

  3. Tandem repeat - Wikipedia

    en.wikipedia.org/wiki/Tandem_repeat

    Tandem repeats can occur through different mechanisms. For example, slipped strand mispairing, (also known as replication slippage), is a mutation process which occurs during DNA replication. It involves denaturation and displacement of the DNA strands, resulting in mispairing of the complementary bases.

  4. Postreplication repair - Wikipedia

    en.wikipedia.org/wiki/Postreplication_repair

    The replication of DNA with a broken sugar-phosphate backbone is most likely facilitated by the homologous recombination proteins that confer resistance to ionizing radiation. The activity of PRR enzymes is regulated by the SOS response in bacteria and may be controlled by the postreplication checkpoint response in eukaryotes.

  5. Reproducibility - Wikipedia

    en.wikipedia.org/wiki/Reproducibility

    Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.

  6. DNA replication stress - Wikipedia

    en.wikipedia.org/wiki/DNA_replication_stress

    The replication fork consists of a group of proteins that influence the activity of DNA replication. In order for the replication fork to stall, the cell must possess a certain number of stalled forks and arrest length. The replication fork is specifically paused due to the stalling of helicase and polymerase activity, which are linked together ...

  7. Try these four expert-approved treat-delivery methods to keep ...

    www.aol.com/try-four-expert-approved-treat...

    “It’s not what you feed, it’s the way you feed it,” explains Burton. “Your treat delivery technique can have a powerful impact on the outcome of your training.”

  8. TikToker Joules Dies After Rare Brain Tumor at 6 Years Old ...

    www.aol.com/tiktoker-joules-dies-rare-brain...

    TikTok creator Joe Smith confirmed that his six-year-old daughter Jules Smith died on Monday, Dec. 9 after she was diagnosed with a fatal brain tumor.. In a video captioned "We love you our little ...

  9. Hayflick limit - Wikipedia

    en.wikipedia.org/wiki/Hayflick_limit

    As the cell divides, the telomeres on the ends of chromosomes shorten. The Hayflick limit is the limit on cell replication imposed by the shortening of telomeres with each division. This end stage is known as cellular senescence. The Hayflick limit has been found to correlate with the length of the telomeric region at the end of chromosomes.