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A glomus tumor (also known as a "solitary glomus tumor" [1]) is a rare neoplasm arising from the glomus body and mainly found under the nail, on the fingertip or in the foot. [2]: 670 They account for less than 2% of all soft tissue tumors. [3] The majority of glomus tumors are benign, but they can also show malignant features. [4]
Studies conducted in the past have also revealed changes in the expression of Bcl-2 and p53 in comparison to benign glomus tumors. [3] [12] These lesions in soft tissue and skin need to be distinguished from other cutaneous round cell malignancies such hemangiopericytoma, leiomyosarcoma, melanoma, and Merkel cell carcinoma. [4] [13]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Treatment: To treat the bites, first wash the lesions with an antibacterial soap. Then, use a skin soothing treatment like calamine lotion to combat the irritation, per the Cleveland Clinic.
Glomus tympanicum and Glomus jugulare, also known as jugulotympanic paraganglioma: Both commonly present as a middle ear mass resulting in tinnitus (in 80%) and hearing loss (in 60%). The cranial nerves of the jugular foramen may be compressed, resulting swallowing difficulty, or ipsilateral weakness of the upper trapezius and ...
A glomus body (or glomus organ; plural glomera) is a component of the dermis layer of the skin, involved in body temperature regulation. [1] [2] The glomus body is a small arteriovenous anastomosis surrounded by a capsule of connective tissue. Glomera are most numerous in the fingers and toes.
Treatment options for soft-tissue sarcomas include surgery, radiotherapy, chemotherapy, and targeted drug therapy. [3] Surgery is the most common treatment for soft-tissue sarcomas, and usually the only way to achieve a cure. The tumor is removed leaving a safe margin of surrounding healthy tissue to decrease the chances of its recurrence.
As the skin lesions are typically painful, it is also often necessary to exclude other painful tumors of the skin (including blue rubber bleb nevus, leiomyoma, eccrine spiradenoma, neuroma, dermatofibroma, angiolipoma, neurilemmoma, endometrioma, glomus tumor and granular cell tumor; the mnemonic "BLEND-AN-EGG" may be helpful).