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Neopentane, also called 2,2-dimethylpropane, is a double-branched-chain alkane with five carbon atoms. Neopentane is a flammable gas at room temperature and pressure which can condense into a highly volatile liquid on a cold day, in an ice bath, or when compressed to a higher pressure.
IAG933 is an investigational new drug that is being evaluated for the treatment of cancer. [1]IAG933 is a small molecule inhibitor developed by Novartis Pharmaceuticals to directly disrupt the YAP/TAZ-TEAD protein-protein interaction, a critical mediator of oncogenic signaling in the Hippo pathway.
Neopentylamine is an organic compound with the molecular formula (CH 3) 3 CCH 2 NH 2. It is a colorless liquid. The molecule is the primary amine derivative of neopentane, (CH 3) 4 C. Like most alkyl amines, it degrades slowly in air. [1]
YK-11 is a synthetic steroidal selective androgen receptor modulator (SARM). [1] [2] It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR.
Neopentyl alcohol is a compound with formula (CH 3) 3 CCH 2 OH. It is a colorless solid. It is a colorless solid. The compound is one of the eight isomers of pentyl alcohol .
Aumolertinib (trade name Ameile) is a pharmaceutical drug for the treatment of cancer. [1] It is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). [2]
The clinical development program for NV-5138 began with a Phase 1 trial initiated by Navitor Pharmaceuticals in 2018. [ 1 ] [ 7 ] This initial study was designed to evaluate the safety, tolerability, and pharmacokinetics of the compound in both healthy volunteers and patients diagnosed with TRD.
Devimistat (INN; development code CPI-613) is an experimental anti-mitochondrial drug being developed by Cornerstone Pharmaceuticals. [1] It is being studied for the treatment of patients with metastatic pancreatic cancer and relapsed or refractory acute myeloid leukemia (AML).