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The term "molecular epidemiology" was first coined by Edwin D. Kilbourne in a 1973 article entitled "The molecular epidemiology of influenza". [5] The term became more formalized with the formulation of the first book on molecular epidemiology titled Molecular Epidemiology: Principles and Practice by Paul A. Schulte and Frederica Perera. [6]
Molecular pathological epidemiology (MPE, also molecular pathologic epidemiology) is a discipline combining epidemiology and pathology. It is defined as "epidemiology of molecular pathology and heterogeneity of disease". [ 1 ]
Epidemiology research to examine the relationship between these biomarkers analyzed at the molecular level and disease was broadly named "molecular epidemiology". Specifically, "genetic epidemiology" has been used for epidemiology of germline genetic variation and disease. Genetic variation is typically determined using DNA from peripheral ...
Shuji Ogino (荻野周史, Ogino Shuji, born April 24, 1968) is a molecular pathological epidemiologist, pathologist, and epidemiologist.He is currently Professor of Pathology at Harvard Medical School and Brigham and Women's Hospital, and Professor in the Department of Epidemiology at Harvard T.H. Chan School of Public Health.
The pathological perspective can be directly integrated into an epidemiological approach in the interdisciplinary field of molecular pathological epidemiology. [6] Molecular pathological epidemiology can help to assess pathogenesis and causality by means of linking a potential risk factor to molecular pathologic signatures of a disease. [7 ...
This framework is well conceptualized in the interdisciplinary field of molecular pathological epidemiology (MPE). [4] [5] Characterize the events as to epidemiological factors Predisposing factors Non-environmental factors that increase the likelihood of getting a disease. Genetic history, age, and gender are examples. Enabling/disabling factors
Functional Molecular Infection Epidemiology (FMIE) [1] is an emerging area of medicine that entails the study of pathogen genes and genomes in the context of their functional association with the host niches (adhesion, invasion, adaptation) and the complex interactions they trigger within the host immune system (cell signaling, apoptosis) to culminate in varied outcomes of the infection.
The crossover between molecular pathology and epidemiology is represented by a related field "molecular pathological epidemiology". [22] Molecular pathology is commonly used in diagnosis of cancer and infectious diseases. Molecular Pathology is primarily used to detect cancers such as melanoma, brainstem glioma, brain tumors as well as many ...