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CSF Fluid Flow MRI detects back and forth flow of Cerebrospinal fluid that corresponds to vascular pulsations from mostly the cardiac cycle of the choroid plexus. Bulk transport of CSF, characterized by CSF circulation through the Central Nervous System , is not used because it is too slow to assess clinically. [ 2 ]
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates.. CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the brain, and absorbed in the arachnoid granulations.
Intracranial pressure (ICP) is the pressure exerted by fluids such as cerebrospinal fluid (CSF) inside the skull and on the brain tissue. ICP is measured in millimeters of mercury and at rest, is normally 7–15 mmHg for a supine adult.
Although the first known observations of the CSF date back to Hippocrates (460–375 BCE) and later, to Galen (130–200 CE), its discovery is credited to Emanuel Swedenborg (1688–1772 CE), who, being a devoutly religious man, identified the CSF during his search for the seat of the soul. [22]
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Proton density (PD)- weighted images are created by having a long repetition time (TR) and a short echo time (TE). [36] On images of the brain, this sequence has a more pronounced distinction between grey matter (bright) and white matter (darker grey), but with little contrast between brain and CSF. [ 36 ]
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