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  2. Optic disc drusen - Wikipedia

    en.wikipedia.org/wiki/Optic_disc_drusen

    A necropsy study of 737 cases showed a 2.4% incidence with 2 out of 15 (13%) bilateral, [2] perhaps indicating the insidious nature of many cases. An autosomal dominant inheritance pattern with incomplete penetrance and associated inherited dysplasia of the optic disc and its blood supply is suspected.

  3. Kjer's optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Kjer's_optic_neuropathy

    Vision loss in dominant optic atrophy is due to optic nerve fiber loss from mitochondria dysfunction. Dominant optic atrophy is associated with mutation of the OPA1 gene [9] found on chromosome 3, region q28-qter. Also, 5 other chromosomal genes are described as causing optic atrophy: OPA2 (x-linked), OPA3 (dominant), OPA4 (dominant), OPA5 ...

  4. Optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Optic_neuropathy

    The optic nerve contains axons of nerve cells that emerge from the retina, leave the eye at the optic disc, and go to the visual cortex where input from the eye is processed into vision. There are 1.2 million optic nerve fibers that derive from the retinal ganglion cells of the inner retina. [ 2 ]

  5. Central serous chorioretinopathy - Wikipedia

    en.wikipedia.org/wiki/Central_serous_chorio...

    Central serous chorioretinopathy (CSC or CSCR), also known as central serous retinopathy (CSR), is an eye disease that causes visual impairment, often temporary, usually in one eye. [ 1 ] [ 2 ] When the disorder is active it is characterized by leakage of fluid under the retina that has a propensity to accumulate under the central macula.

  6. Toxic and nutritional optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Toxic_and_nutritional...

    Vision loss in toxic and nutritional optic neuropathy is bilateral, symmetric, painless, gradual, and progressive. Dyschromatopsia, a change in color vision, is often the first symptom. Some patients notice that certain colors, particularly red, are less bright or vivid; others have a general loss of color perception.

  7. North Carolina macular dystrophy - Wikipedia

    en.wikipedia.org/wiki/North_Carolina_macular...

    North Carolina macular dystrophy is an extremely rare autosomal dominant genetic disorder that primarily affects the eyes. It is a non-progressive disorder which is characterized by an abnormal development of the macula, multiple drusen, photoreceptor cells atrophy, and central vision loss. [2]

  8. Familial exudative vitreoretinopathy - Wikipedia

    en.wikipedia.org/wiki/Familial_exudative_vitreo...

    The retina is the layer of tissue at the back of the eye that receives light and converts it into a signal which travels along the optic nerve to be processed into visual perception by the brain. Familial exudative vitreoretinopathy (FEVR, pronounced as fever) is a genetic disorder affecting the growth and development of blood vessels in the ...

  9. Drusen - Wikipedia

    en.wikipedia.org/wiki/Drusen

    Macular hard drusen in the right eye. 65-year-old diabetic woman. Drusen , from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye .

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