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Intravenous iron therapy has an established role in the treatment of iron deficiency anaemia when oral supplements are ineffective or cannot be used. [12] IV iron infusions can administer the exact dose of iron to normalise levels in the blood. [7] Pre-operative anaemia is associated with high risk of death.
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Low-certainty evidence suggests that IBD-related anemia treatment with Intravenous (IV) iron infusion may be more effective than oral iron therapy, with fewer people needing to stop treatment early due to adverse effects. [54] The type of iron preparation may be an important determinant of clinical benefit.
Chelation therapy removes iron from the blood. [5] This involves delivering iron chelating agents such as deferoxamine, deferiprone or deferasirox. [5] If iron overload has caused damage to end-organs, this is generally irreversible and may require transplantation. [clarification needed]
Iron preparation is the formulation for iron supplements indicated in prophylaxis and treatment of iron-deficiency anemia. Examples of iron preparation include ferrous sulfate, ferrous gluconate, and ferrous fumarate. It can be administered orally, and by intravenous injection, or intramuscular injection. [1] Early Iron Supplement for Anemia
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Iron sucrose is a dark brown liquid solution. It is administered intravenously and is only used when a patient with iron deficiency cannot be treated using oral iron options. [5] It is a generally effective drug, with more than 80% of patients responding to treatment. Iron sucrose has ~20 mg of iron per mL of solution.
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