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Disadvantages of mitotane as a treatment include the side effects and the requirement for blood test monitoring. Issues can arise when too much of the adrenal cortex becomes eroded. Approximately 30% of dogs will experience a reaction in response to treatment with mitotane; prednisone may be used as an antidote. In the event of a reaction ...
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
Glucocorticoid drugs currently being used act nonselectively, so in the long run they may impair many healthy anabolic processes. To prevent this, much research has been focused recently on the elaboration of selectively acting glucocorticoid drugs. Side effects include: Immunodeficiency (see section below)
Dogs get ample correct nutrition from their natural, normal diet; wild and feral dogs can usually get all the nutrients needed from a diet of whole prey and raw meat. In addition, a human diet is not ideal for a dog: the concept of a "balanced" diet for a facultative carnivore like a dog is not the same as in an omnivorous human. Dogs will ...
High volume hypernatremia can be due to hyperaldosteronism, excessive administration of intravenous normal saline or sodium bicarbonate, or rarely from eating too much salt. [1] [2] Low blood protein levels can result in a falsely high sodium measurement. [4] The cause can usually be determined by the history of events. [1]
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Current cure rates using stem cell therapy in dogs approximates that achieved in humans, 40-50%. When cost is a factor, prednisone used alone can improve the symptoms dramatically, but it does not significantly affect the survival rate. The average survival times of dogs treated with prednisone and untreated dogs are both one to two months. [1]
[11] [50] [51] [10] Diabetic dogs require insulin therapy, [52] which must be continued for life. [11] [53] The goal of treatment is to regulate blood glucose using insulin and some probable diet and daily routine changes. [54] The process may take a few weeks or many months and is similar as in type 1 diabetic humans.