Search results
Results from the WOW.Com Content Network
The term "ortholog" was coined in 1970 by the molecular evolutionist Walter Fitch. [41] Homologous sequences are paralogous if they were created by a duplication event within the genome. For gene duplication events, if a gene in an organism is duplicated, the two copies are paralogous. They can shape the structure of whole genomes and thus ...
Human angiogenin diverged from ribonuclease, for example, and while the two paralogs remain similar in tertiary structure, their functions within the cell are now quite different. [ citation needed ] It is often asserted that orthologs are more functionally similar than paralogs of similar divergence, but several papers have challenged this notion.
Orthology (biology) - homologous sequences originate from the same ancestors (homolog e.g. all globin protein), which are separated from each other after a speciation event, e.g. human beta and chimp beta globin. An orthologous gene is a gene in different species that evolved from a common ancestor by speciation.
Homology (anthropology), analogy between human beliefs, practices or artifacts owing to genetic or historical connections; Homology (psychology), behavioral characteristics that have common origins in either evolution or development
Some basic conventions, such as (1) that animal/human homolog (ortholog) pairs differ in letter case (title case and all caps, respectively) and (2) that the symbol is italicized when referring to the gene but nonitalic when referring to the protein, are often not followed by contributors to medical journals.
Human behavior is the potential and expressed capacity (mentally, physically, and socially) of human individuals or groups to respond to internal and external stimuli throughout their life. Behavior is driven by genetic and environmental factors that affect an individual.
DAF-16 is the sole ortholog of the FOXO family of transcription factors in the nematode Caenorhabditis elegans. [1] It is responsible for activating genes involved in longevity, lipogenesis, heat shock survival and oxidative stress responses.
Human Mouse (ortholog) BioGPS: Gene ontology; Molecular function: Cellular component ... Pumilio homolog 1 is a protein that in humans is encoded by the PUM1 gene. [4 ...