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Rubella infection in pregnancy can result in various outcomes ranging from asymptomatic infection to congenital defects to miscarriage and fetal death. [3] [4] If infection occurs 0–11 weeks after conception, the infant has a 90% risk of being affected. [1] If the infection occurs 12–20 weeks after conception, the risk is 20%.
Rubella, also known as German measles or three-day measles, [6] is an infection caused by the rubella virus. [3] This disease is often mild, with half of people not realizing that they are infected. [1] [7] A rash may start around two weeks after exposure and last for three days. [1] It usually starts on the face and spreads to the rest of the ...
Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy. Rubella virus, scientific name Rubivirus rubellae, is a member of the genus Rubivirus and belongs to the ...
Typically, the virus is transmitted via droplets, such as coughing or sneezing, however, congenital rubella can be passed on from a pregnant woman to her fetus. The disease itself is fairly mild, usually presenting with a rash on the face and general sickness symptoms, such as coughing, fever, and fatigue, however, the real danger lies in ...
As the embryo develops, the risk of abnormalities decreases. If exposed to the rubella virus during the first four weeks, the risk of malformations is 47%. Exposure during weeks five through eight creates a 22% chance, while weeks 9–12, a 7% chance exists, followed by 6% if the exposure is during the 13th-16th weeks.
Women who are planning to become pregnant are recommended to have rubella immunity beforehand, as the virus has a potential to cause miscarriage or serious birth defects. [5] Immunity may be verified by pre-pregnancy blood test, and it is recommended that those with negative results should refrain from getting pregnant for at least a month ...
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Rubella, or German measles, is an infection caused by the rubella virus. In childhood, it usually causes a mild disease but infection in pregnancy can result in fetal infection, or congenital rubella syndrome, which causes neonatal deaths, deafness, blindness and intellectual disabilities. The first rubella vaccine was licensed for use in 1969 ...