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[1] [9] [10] It is mainly used in the treatment of heartburn and peptic ulcers. [1] [10] [11] With the development of proton pump inhibitors, such as omeprazole, approved for the same indications, cimetidine is available as an over-the-counter formulation to prevent heartburn or acid indigestion, along with the other H2-receptor antagonists. [12]
They are mediators and have a variety of strong physiological effects, such as regulating the contraction and relaxation of smooth muscle tissue. [8] There are many prostaglandins with many effects. Prostaglandin E2 has effects including reducing gastric acid and increasing gastric mucus, which among other effects treat acid-related disorders. [9]
If you get acid reflux, an upset stomach, or other digestive issues after taking Cialis, making small changes — like drinking more water or using antacid medicine — can make this side effect ...
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
Dr. Vincent M. Pedre III, MD, FMCP, says acid reflux, also known as gastroesophageal reflux disease (GERD), is a condition that affects up to 20 percent of the American population. Some sources ...
Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4]
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3579 S High St, Columbus, OH · Directions · (614) 409-0683