Search results
Results from the WOW.Com Content Network
Cross-links. Crosslinking of DNA; Free radicals – atom, molecule, or ion that has unpaired valence electrons. With some exceptions, these unpaired electrons make free radicals highly chemically reactive towards other substances, or even towards themselves: their molecules will often spontaneously dimerize or polymerize if they come in contact with each other.
Stem cell theory of aging; Stereotype embodiment theory; T. Telomere theory of aging; V. Vital substance theory of aging; W. Waste product accumulation theory of aging;
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Help; Learn to edit; Community portal; Recent changes; Upload file
The theory that DNA damage is the primary cause of aging is based, in part, on evidence in human and mouse that inherited deficiencies in DNA repair genes often cause accelerated aging. [ 29 ] [ 30 ] [ 27 ] There is also substantial evidence that DNA damage accumulates with age in mammalian tissues, such as those of the brain, muscle, liver and ...
The somatic mutation theory of ageing states that accumulation of mutations in somatic cells is the primary cause of aging. A comparison of somatic mutation rate across several mammal species found that the total number of accumulated mutations at the end of lifespan was roughly equal across a broad range of lifespans. [ 16 ]
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. The hallmarks of aging are the types of biochemical changes that occur in all organisms that experience biological aging and lead to a progressive loss of physiological integrity, impaired function and, eventually, death.
Put the phone down and grab a book. Whether you prefer a steamy romance novel, a fascinating piece of nonfiction, or a moody mystery, reading boasts tons of benefits for your brain.
In 1968 it took the form and became known as the neuroendocrine theory of aging. [38] [39] [40] 1956 Denham Harman proposed the free-radical theory of aging and demonstrated that free radical reactions contribute to the degradation of biological systems. [41] The theory is based on the ideas of Rebeca Gerschman and her colleagues put forward in ...