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Another serious and disabling side effect of aminoglycoside use is vestibular ototoxicity. [19] This leads to oscillopsia (gaze instability) and balance impairments that impact all aspects of an individual's antigravity function. This loss is permanent and can happen at any dose. [21] [22] [23] [24]
Side-effects of amikacin are similar to those of other aminoglycosides. Kidney damage and ototoxicity (which can lead to hearing loss) are the most important effects, occurring in 1–10% of users. [17] The nephro- and ototoxicity are thought to be due to aminoglycosides' tendency to accumulate in the kidneys and inner ear. [8] Diagram of the ...
Serious side effects include ringing in the ears or loss of hearing, toxicity to kidneys, and allergic reactions to the drug. [11] Ototoxicity is a common quality among aminoglycosides, and its rate of incidence in kanamycin is around 3-10%. [12] Other side effects include: [9] Gastrointestinal effects Nausea, vomiting, diarrhea ...
Common side effects include vertigo, vomiting, numbness of the face, fever, and rash. [3] Use during pregnancy may result in permanent deafness in the developing baby. [3] Use appears to be safe while breastfeeding. [4] It is not recommended in people with myasthenia gravis or other neuromuscular disorders. [4] Streptomycin is an aminoglycoside ...
Common uses [4] Possible side effects [4] Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All aminoglycosides are ineffective when ...
Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
Less-common side effects can include excess air or gas in your stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy and fatigue, or even gallstones, Dr. Comite says.
Gentamicin should not be used if a person has a history of hypersensitivity, such as anaphylaxis, or other serious toxic reaction to gentamicin or any other aminoglycosides. [15] Greater care is required in people with myasthenia gravis and other neuromuscular disorders as there is a risk of worsening weakness. [ 5 ]
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