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Mydriasis is the dilation of the pupil, usually having a non-physiological cause, [3] or sometimes a physiological pupillary response. [4] Non-physiological causes of mydriasis include disease , trauma , or the use of certain types of drug .
Toggle Causes subsection. 1.1 Age. 1.2 Diseases. ... mydriasis, is the dilation of ... a sign of altered level of consciousness caused by the sedative effect of the drug.
A human adult exhibiting voluntary control over his iris muscles, where he can cause his pupil to dilate and constrict on command A dilation response ( mydriasis ), is the widening of the pupil and may be caused by adrenaline ; anticholinergic agents; stimulant drugs such as MDMA , cocaine , and amphetamines ; and some hallucinogenics (e.g. LSD ...
Tropicamide is an antimuscarinic drug that produces short acting mydriasis (dilation of the pupil) and cycloplegia [7] when applied as eye drops. It is used to allow better examination of the lens, vitreous humor, and retina.
When cycloplegic drugs are used as a mydriatic to dilate the pupil, the pupil in the normal eye regains its function when the drugs are metabolized or carried away. Some cycloplegic drugs can cause dilation of the pupil for several days.
Anticholinergic drugs are used to treat a variety of conditions: Dizziness (including vertigo and motion sickness-related symptoms) Extrapyramidal symptoms, a potential side-effect of antipsychotic medications; Gastrointestinal disorders (e.g., peptic ulcers, diarrhea, pyloro spasm, diverticulitis, ulcerative colitis, nausea, and vomiting)
Most drugs with parasympatholytic properties are anticholinergics. Parasympatholytic agents and sympathomimetic agents have similar effects to each other, although some differences between the two groups can be observed. For example, both cause mydriasis, but parasympatholytics reduce accommodation (cycloplegia), whereas sympathomimetics do not.
Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. [15] Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ...