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  2. Aseptic processing - Wikipedia

    en.wikipedia.org/wiki/Aseptic_processing

    Equipment used in aseptic processing of food and beverages must be sterilized before processing and remain sterile during processing. [1] When designing aseptic processing equipment there are six basic requirements to consider: the equipment must have the capability of being cleaned thoroughly, it must be able to be sterilized with steam, chemicals, or high-temperature water, sterilization ...

  3. Autoclave - Wikipedia

    en.wikipedia.org/wiki/Autoclave

    Incineration or a similar thermal oxidation process is still generally mandated for pathological waste and other very toxic or infectious medical waste. For liquid waste, an effluent decontamination system is the equivalent hardware. In dentistry, autoclaves provide sterilization of dental instruments.

  4. Closed system drug transfer device - Wikipedia

    en.wikipedia.org/wiki/Closed_system_drug...

    A closed system drug transfer device or "CSTD" is a drug transfer device that mechanically prohibits the transfer of environmental contaminants into a system and the escape of hazardous drug or vapor concentrations outside the system. Open versus closed systems are commonly applied in medical devices to maintain the sterility of a fluid pathway.

  5. Sterility assurance level - Wikipedia

    en.wikipedia.org/wiki/Sterility_assurance_level

    So SAL is used to express the probability of the survival. For example, medical device manufacturers design their sterilization processes for an extremely low SAL, such as 10 −6, which is a 1 in 1,000,000 chance of a non-sterile unit. SAL also describes the killing efficacy of a sterilization process.

  6. Blow fill seal - Wikipedia

    en.wikipedia.org/wiki/Blow_fill_seal

    BFS-packaged eye drops for single use. Blow-Fill-Seal, also spelled as Blow/Fill/Seal, in this article abbreviated as BFS, is an automated manufacturing process by which plastic containers, such as bottles or ampoules are, in a continuous operation, blow-formed, filled, and sealed.

  7. Central sterile services department - Wikipedia

    en.wikipedia.org/wiki/Central_sterile_services...

    Sterile dental instruments from hospital central supply (barcoded label indicating sterilization date, expiry date and contents). The central sterile services department (CSSD), also called sterile processing department (SPD), sterile processing, central supply department (CSD), or central supply, is an integrated place in hospitals and other health care facilities that performs sterilization ...

  8. Cleanroom - Wikipedia

    en.wikipedia.org/wiki/Cleanroom

    With such a wide area of application, not every cleanroom is the same. For example, the rooms utilized in semiconductor manufacturing need not be sterile (i.e., free of uncontrolled microbes), [8] while the ones used in biotechnology usually must be.

  9. Grand River Aseptic Manufacturing - Wikipedia

    en.wikipedia.org/wiki/Grand_River_Aseptic...

    Grand River Aseptic Manufacturing (GRAM) is a clinical and commercial sterile manufacturing contractor to the pharmaceutical industry. It has lyophilization , terminal sterilization, analytical, microbiological testing services.