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Smooth muscle is grouped into two types: single-unit smooth muscle, also known as visceral smooth muscle, and multiunit smooth muscle. Most smooth muscle is of the single-unit type, and is found in the walls of most internal organs (viscera); and lines blood vessels (except large elastic arteries), the urinary tract , and the digestive tract .
Muscle fibers contain numerous tubular myofibrils. Myofibrils are composed of repeating sections of sarcomeres, which appear under the microscope as alternating dark and light bands. Sarcomeres are composed of long, fibrous proteins as filaments that slide past each other when a muscle contracts or relaxes.
Structure of muscle fibre (sarcomere) under electron microscope with schematic explanation. By the time Hugh Huxley earned his PhD from the University of Cambridge in 1952 on his research on the structure of muscle, Szent-Györgyi had turned his career into cancer research. [12]
In the skin, smooth muscle cells such as those of the arrector pili cause hair to stand erect in response to cold temperature or fear. [19] Smooth muscle cells are spindle-shaped with wide middles, and tapering ends. They have a single nucleus and range from 30 to 200 micrometers in length. This is thousands of times shorter than skeletal ...
In 1969, Don Fawcett labelled these cells as ‘peritubular myoid cells’. ‘Peritubular’ refers to their anatomical location: adjacent to the seminiferous tubule. ‘Myoid’ stems from the Greek ‘myo’ (/ˈmʌɪəʊ/), which means relating to muscle. (PTMs resemble smooth muscle cells under an electron microscope). [2]
The submucosa (or tela submucosa) is a thin layer of tissue in various organs of the gastrointestinal, respiratory, and genitourinary tracts. It is the layer of dense irregular connective tissue that supports the mucosa (mucous membrane) and joins it to the muscular layer, the bulk of overlying smooth muscle (fibers running circularly within layer of longitudinal muscle).
Vascular smooth muscle cells also play important roles during development, e.g. driving osteocyte differentiation from undifferentiated precursors during osteogenesis. [1] Arteries have a great deal more smooth muscle within their walls than veins, thus their greater wall thickness. This is because they have to carry pumped blood away from the ...
The fibres of striated muscle have a cylindrical shape with blunt ends, whereas those in smooth muscle are spindle-like with tapered ends. Striated muscle tissue has more mitochondria than smooth muscle. Both smooth muscle cells and cardiac muscle cells have a single nucleus, and skeletal muscle cells have many nuclei. [6]