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The Dengvaxia controversy (locally [dɛŋˈvakʃa]) occurred in the Philippines when the dengue vaccine Dengvaxia was found to increase the risk of disease severity for some people who had received it. [1] [2] A vaccination program run by the Philippine Department of Health (DOH) administered Sanofi Pasteur's Dengvaxia to schoolchildren. [3]
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
The 2019–2020 dengue fever epidemic was an epidemic of the infectious disease dengue fever in several countries of Southeast Asia, including the Philippines, Malaysia, Vietnam, and Bangladesh, [1] Pakistan, [2] India, Thailand, Singapore, and Laos. [3]
Pineda-Cortel focuses her research on early-detection and diagnosis of GDM in pregnant women in the Philippines. The prevalence of GDM in the Philippines is around 30%, and Pineda-Cortel aims to increase accessibility and availability of standard diagnostic and screening tests for GDM to prevent further health complications in the mother and the baby. [4]
Over the last twenty years, there has been a geographic spread of the disease. Dengue incidence rates have risen sharply within urban areas which have recently become endemic hot spots for the disease. [61] The recent spread of Dengue can also be attributed to rapid population growth, increased coagulation in urban areas, and global travel.
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
65,758 cases of dengue fever have been reported up to EW 19 in Mexico, accounting for 0.8% of total cases in Latin America and the Caribbean in 2024. 405 severe cases and 20 deaths have been reported so far in Mexico, with a fatality rate of 0.03%.
Dengue fever is caused by a virus transmitted by mosquitoes which are born in still water. Due to water shortages, households are forced to store water throughout the year. Espino’s research team engaged the local Barangay Health Workers (BHWs) to introduce a household water container management system to control dengue in 2 communities in ...