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The most common side effects in the absence of alcohol are headache, and a metallic or garlic taste in the mouth, though more severe side effects may occur. [10] Tryptophol, a chemical compound that induces sleep in humans, is formed in the liver after disulfiram treatment. [11]
Because medications have been linked to approximately 22% to 28% of all cases of dysgeusia, researching a treatment for this particular cause has been important. [39] Xerostomia, or a decrease in saliva flow, can be a side effect of many drugs, which, in turn, can lead to the development of taste disturbances such as dysgeusia. [39]
Common side effects include diarrhea, nausea and dysgeusia (distortion of the sense of taste), especially a metallic taste. These effects are known from the drug's components as well as from other antibiotics.
Common side effects include nausea, a metallic taste, loss of appetite, and headaches. [10] Occasionally seizures or allergies to the medication may occur. [10] Some state that metronidazole should not be used in early pregnancy, while others state doses for trichomoniasis are safe.
The metronidazole tablet may have an unpleasant metallic taste, deteriorating drug compliance. [47] This medication may also induce rare side effect in the central nervous system, including neurotoxicity (encephalopathy, peripheral neuropathy, seizure). [48] [49] [50] [51]
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Less common side effects (<1%) include extreme irritability, hallucinations (auditory and visual), dizziness/motion sickness, and alteration in senses of smell and taste, including a metallic taste. Dry mouth, panic attacks, and nightmares have also been reported, albeit less frequently. [13]
The side effects encountered are anorexia, nausea, diarrhea, metallic taste, and weight loss. Its use is contraindicated in diabetic coma, ketoacidosis, severe infection, trauma, other conditions where buformin is unlikely to control the hyperglycemia, renal or hepatic impairment, heart failure, recent myocardial infarct, dehydration ...