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Buspirone, sold under the brand name Buspar, among others, is an anxiolytic, a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder (GAD). [ 10 ] [ 11 ] It is a serotonin 5-HT 1A receptor partial agonist , increasing action at serotonin receptors in the brain. [ 3 ]
People affected by anxiety and depression are believed (at least in part) to have altered levels of serotonin. ... Buspirone. Buspirone is an azapirone medication that’s used to treat certain ...
SSRIs are beneficial in both acute response and long-term maintenance treatment for both depression and anxiety disorder. [16] SSRIs can increase anxiety initially due to negative feedback through the serotonergic autoreceptors; for this reason a concurrent benzodiazepine can be used until the anxiolytic effect of the SSRI occurs. [18]
Buspar – an anxiolytic used to treat generalized anxiety disorder; Belbuca, Buprenex, Butrans, Subutex, Probuohine (buprenorphine) - an opioid medicine used to treat moderate to severe pain, and in some formulations to treat opioid use disorder; Belsomra – used to treat insomnia
5-HT 1A receptor agonists like buspirone [18] and flesinoxan [19] show efficacy in relieving anxiety [20] and depression. [21] Buspirone and tandospirone are currently approved for these indications in different parts of the world.
Key symptoms include excessive anxiety about multiple events and issues, and difficulty controlling worrisome thoughts, that persists for at least 6 months. Antidepressants provide a modest-to-moderate reduction in anxiety in GAD, [25] and are superior to placebo in treating GAD. The efficacy of different antidepressants is similar.
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