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  2. Dimenhydrinate - Wikipedia

    en.wikipedia.org/wiki/Dimenhydrinate

    Dimenhydrinate is an over-the-counter (OTC) first-generation antihistamine indicated for the prevention and relief of nausea and vomiting from a number of causes, including motion-sickness and post-operative nausea. [2] Dimenhydrinate can also be used for Insomnia, but this is an off label use. [5]

  3. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    Its effects on central H 1 receptors cause drowsiness. Diphenhydramine is a potent antimuscarinic (a competitive antagonist of muscarinic acetylcholine receptors) and, as such, at high doses can cause anticholinergic syndrome. [68]

  4. H1 antagonist - Wikipedia

    en.wikipedia.org/wiki/H1_antagonist

    Dimenhydrinate; Alkylamines: The isomerism is a significant factor in the activity of the agents in this group. E-triprolidine, for example, is 1000-fold more potent than Z-triprolidine. This difference relates to the positioning and fit of the molecules in the histamine H 1-receptor binding site. [15]

  5. Traveling can be exhausting: How to prevent this debilitating ...

    www.aol.com/traveling-exhausting-prevent...

    Travelers can also turn to medications like Dramamine or Benadryl, which Adamian recommended taking 30 to 60 minutes in advance (though she noted they cause drowsiness). Those can also help ...

  6. These Anti-Motion Sickness Glasses Are Going Viral on ... - AOL

    www.aol.com/anti-motion-sickness-glasses-going...

    However, both scopolamine and antihistamines can cause drowsiness and sedation, Dr. Strachan warns — meaning that it's best to avoid these options if you're driving or traveling alone for longer ...

  7. Benadryl - Wikipedia

    en.wikipedia.org/wiki/Benadryl

    Diphenhydramine has a common side effect of drowsiness or sleepiness. [12] Because of these sedative properties, Benadryl is often used as a sleep aid in people with insomnia . A study published in the American Journal of Geriatric Psychiatry discovered that approximately one in three adults between the ages of 65 and 80 occasionally use over ...

  8. Antihistamine - Wikipedia

    en.wikipedia.org/wiki/Antihistamine

    The evidence does not report how antihistamines affect women differently than men. [1] Different studies have reported on antihistamine use in children, with various studies finding evidence that certain antihistamines could be used by children 2 years of age, and other drugs being safer for younger or older children.

  9. 8-Chlorotheophylline - Wikipedia

    en.wikipedia.org/wiki/8-Chlorotheophylline

    Diphenhydramine reduces nausea but causes drowsiness, and the stimulant properties of 8-Chlorotheophylline help reduce that side effect. [2] Despite being classified as a xanthine stimulant, 8-chlorotheophylline can generally not produce any locomotor activity above control in mice and does not appear to cross the blood-brain barrier well.