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The similarity-based [4] virtual screening (a kind of ligand-based virtual screening) assumes that all compounds in a database that are similar to a query compound have similar biological activity. Although this hypothesis is not always valid, [ 5 ] quite often the set of retrieved compounds is considerably enriched with actives. [ 6 ]
Li is the only group 1 element which forms a stable nitride, Li 3 N. [4] Mg, as well as other group 2 elements, also form nitrides. [4] Lithium carbonate, phosphate and fluoride are sparingly soluble in water. The corresponding group 2 salts are insoluble. (Think lattice and solvation energies). Both Li and Mg form covalent organometallic compounds
The ΔH° form undergoes discontinuities at a phase transition temperatures of the constituent element(s) and the compound. The enthalpy change for any standard reaction is designated ΔH° rx. Standard molar heat of formation of ZnBr 2 (c,l) from the elements, showing discontinuities at transition temperatures of the elements and the compound.
Elements in the same group tend to show similar chemical characteristics. Vertical, horizontal and diagonal trends characterize the periodic table. Metallic character increases going down a group and from right to left across a period. Nonmetallic character increases going from the bottom left of the periodic table to the top right.
Elements that fall close to each other on the periodic table tend to have similar electronegativities, which means they have a similar affinity for electrons. Since neither element has a stronger affinity to donate or gain electrons, it causes the elements to share electrons so both elements have a more stable octet .
In the f-block and p-block of the periodic table, elements within the same period generally do not exhibit trends and similarities in properties (vertical trends down groups are more significant). However, in the d-block, trends across periods become significant, and in the f-block elements show a high degree of similarity across periods.
The unusual compound Ge 6 Cl 16 has been prepared that contains the Ge 5 Cl 12 unit with a neopentane structure. [50] Germane (GeH 4) is a compound similar in structure to methane. Polygermanes—compounds that are similar to alkanes—with formula Ge n H 2n+2 containing up to five germanium atoms are known. [42]
A single-displacement reaction, also known as single replacement reaction or exchange reaction, is an archaic concept in chemistry.It describes the stoichiometry of some chemical reactions in which one element or ligand is replaced by atom or group.
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