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Orotic acid (/ ɔː ˈ r ɒ t ɪ k /) [1] is a pyrimidinedione and a carboxylic acid.Historically, it was believed to be part of the vitamin B complex and was called vitamin B 13, but it is now known that it is not a vitamin.
Coupled together vitamin B 12 and haptocorrin create a complex. This haptocorrin–B 12 complex is impervious to the insult of the stomach acid, and passes on via the pylorus to the duodenum. In the duodenum pancreatic proteases (a component of pancreatic juice) cleave haptocorrin, releasing vitamin B 12 in its free form.
The relationship between the amount of vitamin B 6 consumed and the serum levels of those who consume it varies between individuals. [52] Some people may have high serum concentrations without neuropathy symptoms. [13] [53] [54] It is not known if inhalation of vitamin B 6 while, for example, working with animal feed containing vitamin B 6 is ...
It’s made up of eight smaller vitamins: thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B6), biotin, folic acid, and ...
The B 12 vitamin is not abundantly available from plant products [4] (although it has been found in moderate abundance in fermented vegetable products, certain seaweeds, and in certain mushrooms, with the bioavailability of the vitamin in these cases remaining uncertain), [5] making B 12 deficiency a legitimate concern for those maintaining a ...
It primarily serves to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a HC-Vitamin B 12 complex. Once the complex has traveled to the more pH-neutral duodenum, pancreatic proteases degrade haptocorrin, releasing free cobalamin, which now binds to intrinsic factor for absorption by ileal enterocytes.
Injection of hydroxocobalamin is used to rectify the following causes of vitamin B 12 deficiency (list taken from the drug prescription label published by the U.S. Food and Drug Administration) Dietary deficiency of vitamin B 12 occurring in strict vegetarians and in their breastfed infants (isolated vitamin B 12 deficiency is very rare)
Mesotherapy involves injecting unregulated mixtures of vitamins and drugs under the skin to reduce under-eye bags Beautician performing a procedure on woman; highlights dangerous beauty trend ...
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