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Griffith's experiment discovering the "transforming principle" in Streptococcus pneumoniae (pneumococcal) bacteria. Griffith's experiment, [1] performed by Frederick Griffith and reported in 1928, [2] was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation.
Considered to be the first acknowledged microscopist. Van Leeuwenhoek was the first to observe microscopic organisms, using simple single-lensed microscopes of his own design. [1] 1729–1799 Lazzaro Spallanzani: Italian Proved that bacteria did not arise due to spontaneous generation by developing a sealed, sterile broth medium. [2] [3] 1749 ...
Ancient societies used moulds to treat infections and in the following centuries many people observed the inhibition of bacterial growth by moulds. While working at St Mary's Hospital in London in 1928, Scottish physician Alexander Fleming was the first to experimentally demonstrate that a Penicillium mould secretes an antibacterial substance ...
This was the first recorded discovery of lysozyme. With Allison, he published further studies on lysozyme in October issue of the British Journal of Experimental Pathology the same year. [ 17 ] Although he was able to obtain larger amounts of lysozyme from egg whites, the enzyme was only effective against small counts of harmless bacteria, and ...
The second half of the 20th century was the golden age of virus discovery and most of the 2,000 recognised species of animal, plant, and bacterial viruses were discovered during these years. [ 58 ] [ 59 ] In 1946, bovine virus diarrhea was discovered, [ 60 ] which is still possibly the most common pathogen of cattle throughout the world [ 61 ...
Heinrich Hermann Robert Koch (/ k ɒ x / KOKH; [1] [2] German: [ˈʁoːbɛʁt ˈkɔx] ⓘ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist.As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he is regarded as one of the main founders of modern bacteriology.
Louis Pasteur ForMemRS (/ ˈ l uː i p æ ˈ s t ɜːr /, French: [lwi pastœʁ] ⓘ; 27 December 1822 – 28 September 1895) was a French chemist, pharmacist, and microbiologist renowned for his discoveries of the principles of vaccination, microbial fermentation, and pasteurization, the last of which was named after him.
He repeated the experiment with the same bacteria-killing results. [ 21 ] [ 24 ] [ 25 ] He concluded that the mould was releasing a substance that was inhibiting bacterial growth. [ 26 ] On testing against different bacteria, he found that the mould could kill only certain Gram-positive bacteria. [ 27 ]