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Considered to be the first acknowledged microscopist. Van Leeuwenhoek was the first to observe microscopic organisms, using simple single-lensed microscopes of his own design. [1] 1729–1799 Lazzaro Spallanzani: Italian Proved that bacteria did not arise due to spontaneous generation by developing a sealed, sterile broth medium. [2] [3] 1749 ...
The lysozyme was first noticed during some investigations made on a patient suffering from acute coryza. [15] This was the first recorded discovery of lysozyme. With Allison, he published further studies on lysozyme in October issue of the British Journal of Experimental Pathology the same year. [17]
He repeated the experiment with the same bacteria-killing results. He later recounted his experience: When I woke up just after dawn on September 28, 1928, I certainly didn't plan to revolutionize all medicine by discovering the world's first antibiotic, or bacteria killer. But I suppose that was exactly what I did. [9]
The evolution of bacteria has progressed over billions of years since the Precambrian time with their first major divergence from the archaeal/eukaryotic lineage roughly 3.2-3.5 billion years ago. [1] [2] This was discovered through gene sequencing of bacterial nucleoids to reconstruct their phylogeny.
Heinrich Hermann Robert Koch (/ k ɒ x / KOKH; [1] [2] German: [ˈʁoːbɛʁt ˈkɔx] ⓘ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist.As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he is regarded as one of the main founders of modern bacteriology.
Griffith's experiment discovering the "transforming principle" in Streptococcus pneumoniae (pneumococcal) bacteria. Griffith's experiment, [1] performed by Frederick Griffith and reported in 1928, [2] was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation.
He repeated the experiment with the same bacteria-killing results. [21] [24] [25] He concluded that the mould was releasing a substance that was inhibiting bacterial growth. [26] On testing against different bacteria, he found that the mould could kill only certain Gram-positive bacteria. [27]
The bacteria from chicken used in the experiment was provided by another researcher Doris Jones, and Elizabeth Bugie performed the antibacterial tests. [16] Schatz, Bugie and Waksman reported the discovery in the journal Experimental Biology and Medicine which published it on 1 January 1944. [17]