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The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts.
Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. [ 3 ] [ 4 ] [ 2 ] Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can ...
Google Maps' location tracking is regarded by some as a threat to users' privacy, with Dylan Tweney of VentureBeat writing in August 2014 that "Google is probably logging your location, step by step, via Google Maps", and linked users to Google's location history map, which "lets you see the path you've traced for any given day that your ...
The protein kinase domain is 330 amino acids long and is located near the N-terminus of the protein. [ 23 ] [ 24 ] In addition to its kinase domain, HIPK2 has two nuclear localization signals, [ 25 ] a SUMO interaction motif, [ 25 ] an auto-inhibitory domain [ 23 ] a transcriptional co-repression domain, [ 13 ] and several interaction domains ...
Democratic Rep. Nancy Pelosi, 84, underwent a successful hip replacement surgery after falling while in Luxembourg with a congressional delegation, her office said Saturday. "Earlier this morning ...
1406 12951 Ensembl ENSG00000105392 ENSMUSG00000041578 UniProt O43186 O54751 RefSeq (mRNA) NM_000554 NM_001113330 NM_007770 RefSeq (protein) NP_000545 NP_001106801 NP_031796 Location (UCSC) Chr 19: 47.82 – 47.84 Mb Chr 7: 15.6 – 15.61 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cone-rod homeobox protein is a protein that in humans is encoded by the CRX gene. Function The ...
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