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Routes of administration are usually classified by application location (or exposition). The route or course the active substance takes from application location to the location where it has its target effect is usually rather a matter of pharmacokinetics (concerning the processes of uptake, distribution, and elimination of drugs).
Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood. Its main focus is on drugs with a narrow therapeutic range , i.e. drugs that can easily be under- or overdosed. [ 1 ]
Lipinski's rule of five, also known as Pfizer's rule of five or simply the rule of five (RO5), is a rule of thumb to evaluate druglikeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would likely make it an orally active drug in humans.
In pharmacology, clearance is a pharmacokinetic parameter representing the efficiency of drug elimination. This is the rate of elimination of a substance divided by its concentration. [ 1 ] The parameter also indicates the theoretical volume of plasma from which a substance would be completely removed per unit time.
Notre Dame quarterback Riley Leonard raised the bar on boyfriend goals after his team's Orange Bowl win on Jan. 9.. During a postgame interview with SiriusXM's Alyssa Lang, Leonard, 22, said he ...
An emergency medical technician (often, more simply, EMT) is a medical professional that provides emergency medical services. [1] [2] EMTs are most commonly found serving on ambulances and in fire departments in the US and Canada, as full-time and some part-time departments require their firefighters to at least be EMT certified.
Nathan Williams, 37, gave the jailbirds docs doused in the mind-bending street drug at Duval County Jail in Jacksonville in exchange for money and bribes, according to local cops.
A national study discovered that teens in the United States consumed significantly less alcohol and drugs in 2024 compared to past years. Teen alcohol use has steadily decreased from 2000 to 2024 ...