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Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
Spermarche, also known as semenarche, is the time at which a male experiences his first ejaculation. [1] It is considered to be the counterpart of menarche in females. [2] [3] Depending on upbringing, cultural differences, and prior sexual knowledge, males may have different reactions to spermarche, ranging from fear to excitement. [4]
In the United States, cenobamate is indicated for the treatment of partial-onset seizures in adults. [3]In the European Union, it is indicated for the adjunctive treatment of focal-onset seizures with or without secondary generalization in adults with epilepsy who have not been adequately controlled despite a history of treatment with at least two anti-epileptic medications.
Early withdrawal penalties ... and Roth IRAs — which for the 2024 tax year is an increased annual contribution limit of $7,000 for those under age 50 and $8,000 for those ages 50 and older ...
Sexual activities involving men who have sex with men (MSM), regardless of their sexual orientation or sexual identity, [1] can include anal sex, non-penetrative sex, and oral sex. Evidence shows that sex between men is significantly underreported in surveys. [2] [3]
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If they’re stored in optimal conditions, you can get the most bang for your buck. Best case scenario, the average shelf-life of vitamins is two years, Davis-Cadogan adds.
Ethosuximide is usually well tolerated. [5] Common side effects include loss of appetite, abdominal pain, diarrhea, and feeling tired. [4] Serious side effects include suicidal thoughts, low blood cell levels, and lupus erythematosus. [4] [5] It is unclear if it has adverse effects on the fetus during pregnancy. [4]