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SARS-CoV-2 is the virus that causes coronavirus disease 2019 (COVID-19). Some have been stated, to be of particular importance due to their potential for increased transmissibility, [1] increased virulence, or reduced effectiveness of vaccines against them. [2] [3] These variants contribute to the continuation of the COVID-19 pandemic.
Coronavirus diseases are caused by viruses in the coronavirus subfamily, a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, the group of viruses cause respiratory tract infections that can range from mild to lethal.
For the Netherlands, based on overall excess mortality, an estimated 20,000 people died from COVID-19 in 2020, [10] while only the death of 11,525 identified COVID-19 cases was registered. [9] The official count of COVID-19 deaths as of December 2021 is slightly more than 5.4 million, according to World Health Organization's report in May 2022 ...
Masitinib was found to inhibit SARS-CoV-2 main protease, showing a greater than 200-fold reduction in viral titers in the lungs and nose of mice, however it is not approved for the treatment of COVID-19 in humans. [168] [needs update] In December 2021, the United States granted emergency use authorization to Nirmatrelvir/ritonavir for the ...
For even more international statistics in table, graph, and map form see COVID-19 pandemic by country. COVID-19 pandemic is the worst-ever worldwide calamity experienced on a large scale (with an estimated 7 million deaths) in the 21st century. The COVID-19 death toll is the highest seen on a global scale since the Spanish flu and World War II.
The large number and global range of bat and avian species that host viruses have enabled extensive evolution and dissemination of coronaviruses. [74] Many human coronaviruses have their origin in bats. [75] The human coronavirus NL63 shared a common ancestor with a bat coronavirus (ARCoV.2) between 1190 and 1449 CE. [76]
Fentanyl has made headlines for driving overdose deaths, but the Centers for Disease Control and Prevention is warning of the rise of an even deadlier drug. An addiction specialist weighs in.
This article documents the chronology and epidemiology of the COVID-19 pandemic, involving coronavirus disease 2019 caused by SARS-CoV-2, in 2023. The WHO ended the public health emergency of international concern (PHEIC) on 5 May 2023. [ 1 ]