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Cholestatic pruritus is the sensation of itch due to nearly any liver disease, but the most commonly associated entities are primary biliary cholangitis, primary sclerosing cholangitis, obstructive choledocholithiasis, carcinoma of the bile duct, cholestasis (also see drug-induced pruritus), and chronic hepatitis C viral infection and other forms of viral hepatitis.
Dry skin and dry eyes are also common. Itching occurs in 20–70% of cases, [4] and can develop at any stage of the disease. Textbooks tend to describe itching in the feet and hands, but patients may also experience itching of the scalp, face, back, or other areas. The itching is typically mild-to-moderate in intensity.
Affected individuals may have no symptoms or may experience signs and symptoms of liver disease, such as yellow discoloration of the skin and eyes, itching, and abdominal pain. The bile duct scarring that occurs in PSC narrows the ducts of the biliary tree and impedes the flow of bile to the intestines.
OTC skin protectants like zinc acetate, zinc carbonate, zinc oxide, and calamine can also help dry the oozing and weeping, while baking soda or colloidal oatmeal may help with the itch, the FDA ...
Although the exact cause of PN is unknown, PN is associated with other dermatologic conditions such as untreated or severe atopic dermatitis and systemic causes of pruritus including liver disease and end stage kidney disease. [2] The goal of treatment in PN is to decrease itching. PN is also known as Hyde prurigo nodularis, or Picker's nodules ...
Finally, any systemic disease that can cause diffuse itching such as lymphoma, liver disease, kidney failure, hypothyroidism, and vitamin A, D, and iron deficiencies may cause anal itching. 14 ...
The possible causes of chronic itch go way beyond dry skin. The post 11 Things Your Itchy Skin Can Reveal About Your Health appeared first on Reader's Digest.
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. [3] [6] Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. [7]
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