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The diagnosis is made by the clinical picture and the chest X-ray, which demonstrates decreased lung volumes (bell-shaped chest), absence of the thymus (after about six hours), a small (0.5–1 mm), discrete, uniform infiltrate (sometimes described as a "ground glass" appearance or "diffuse airspace and interstitial opacities") that involves ...
Transient tachypnea of the newborn occurs in approximately 1 in 100 preterm infants and 3.6–5.7 per 1000 term infants. It is most common in infants born by caesarian section without a trial of labor after 35 weeks of gestation. Male infants and infants with an umbilical cord prolapse or perinatal asphyxia are at higher risk.
The donor blood undergoes leukapheresis, a process by which white blood cells are separated from red blood cells and plasma. During the blood collection, the donor's blood is mixed with hydroxyethyl starch , which helps separate the granulocytes from other blood components during sample processing.
Ground-glass opacity is in contrast to consolidation, in which the pulmonary vascular markings are obscured. [3] [5] GGO can be used to describe both focal and diffuse areas of increased density. [5] Subtypes of GGOs include diffuse, nodular, centrilobular, mosaic, crazy paving, halo sign, and reversed halo sign. [6]
Blood banks use a donor history questionnaire to screen for people who have had malaria or who lived in a country where the disease is endemic in the past three years.
Diffuse alveolar damage (DAD) is a histologic term used to describe specific changes that occur to the structure of the lungs during injury or disease. Most often DAD is described in association with the early stages of acute respiratory distress syndrome ( ARDS ). [ 1 ]
When these are subjected to immunofluorescence, three patterns can be observed: linear, granular and negative (pauci-immune). [1] The linear and granular patterns are examples of positive immunofluorescence that are associated as follows: Goodpasture syndrome (linear pattern), post-streptococcal glomerulonephritis (granular), and diffuse ...
There are four types of histopathologic patterns seen in ILD: usual interstitial pneumonia, non-specific interstitial pneumonia, organizing pneumonia, and diffuse alveolar damage. [8] There is significant overlap of the histopathological and radiologic features of each ILD type making diagnosis challenging; even with lung biopsy, 15% of cases ...