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Pomalidomide, sold under the brand names Pomalyst and Imnovid, [7] [8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma. [ 7 ] Pomalidomide was approved for medical use in the United States in February 2013, [ 10 ] and in the European Union in August 2013. [ 8 ]
It is the most common bacterial pneumonia found in adults, the most common type of community-acquired pneumonia, and one of the common types of pneumococcal infection. The estimated number of Americans with pneumococcal pneumonia is 900,000 annually, with almost 400,000 cases hospitalized and fatalities accounting for 5-7% of these cases. [2]
Oral Anti-Cancer Therapy Pomalidomide Celgene Receives Positive CHMP Opinion as Treatment for Patients with Relapsed and Refractory Multiple Myeloma BOUDRY, Switzerland--(BUSINESS WIRE)-- Celgene ...
Fatigue, diarrhea, pyrexia, constipation, cough, peripheral neuropathy, nasopharyngitis, upper respiratory tract infection, decreased appetite, and pneumonia; Similarly, the adverse reactions in the Eloquent 3 trial were examined by comparing the elotuzumab combined with pomalidomide and dexamethasone with the pomalidomide and dexamethasone alone.
Doctors have long urged people ages 50 and older to get a shot to protect against bacterial pneumonia.
By 2004, all-cause pneumonia admission rates had declined by 39% (95% CI 22–52) and rates of hospitalizations for pneumococcal meningitis decreased by 66% (95% CI 56.3–73.5) in children younger than 2. [61] [62] Rates of invasive pneumococcal disease among adults have also declined since the introduction of the vaccine. [54] [62]
What can we do to protect ourselves? Rajendram recommends people talk with their physician about vaccines during checkups. He suggests everyone ages 6 months and older get the flu shot.
While pneumonia is a localized infection, pneumonitis is widespread. [3] A spirometer may also be used to measure pulmonary function. During external examination, clubbing (swelling of fingertip tissue and increase in angle at the nail bed), [14] and basal crackles may be observed.
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