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Myrcludex B is a synthetic N-acylated pre-S1 [11] [12] that can also dock to NTCP, blocking the virus's entry mechanism. [13] The drug is also effective against hepatitis D because the hepatitis D virus uses the same entry receptor as HBV and is only effective in the presence of a hepatitis B virus infection. [13]
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The next month, Tekmira changed its name to Arbutus Biopharma and said that it would focus on drugs to treat hepatitis B. [11] [19] In March 2017 Arbutus signed another license for its liposome delivery technology, this time with Alexion Pharmaceuticals, for delivery of an mRNA drug candidate. [12]
Hepatitis C Sofosbuvir: Hepatitis C [17] nucleoside analogue reverse transcriptase inhibitor: Stavudine: HIV Taribavirin (Viramidine) Hepatitis Syndromes in which Ribavirin is active [18] Telaprevir: Hepatitis C Telbivudine (Tyzeka) Hepatitis B: Tenofovir alafenamide: Hepatitis B: Tenofovir disoproxil: Hepatitis B, HIV [19] Tipranavir: HIV ...
A hexavalent vaccine, or 6-in-1 vaccine, is a combination vaccine with six individual vaccines conjugated into one, intended to protect people from multiple diseases. [1] [9] The term usually refers to the children's vaccine that protects against diphtheria, tetanus, pertussis, poliomyelitis, haemophilus B, and hepatitis B, [1] [9] which is used in more than 90 countries around the world ...
Ombitasvir/paritaprevir/ritonavir could cause hepatitis B re-activation in people co-infected with hepatitis B and C viruses. The European Medicines Agency recommended screening all people for hepatitis B before starting ombitasvir/paritaprevir/ritonavir for hepatitis C in order to minimize the risk of hepatitis B reactivation.
Telbivudine is an antiviral drug used in the treatment of hepatitis B infection. It is marketed by Swiss pharmaceutical company Novartis under the trade names Sebivo (European Union) and Tyzeka (United States). Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance.
Lobucavir has been shown to exhibit antiviral activity against herpesvirus, hepatitis B, HIV/AIDS, and human cytomegalovirus. [6] It reached phase III clinical trials for hepatitis B and herpesvirus, phase II clinical trials for cytomegalovirus, and underwent a pilot study for use in treating AIDs [7] [8] prior to discontinuation.
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