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  2. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Opioid use disorder (OUD) is a substance use disorder characterized by cravings for opioids, continued use despite physical and/or psychological deterioration, increased tolerance with use, and withdrawal symptoms after discontinuing opioids. Opioid withdrawal symptoms include nausea, muscle aches, diarrhea, trouble sleeping, agitation, and a ...

  3. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Opiate overdose symptoms and signs can be referred to as the "opioid toxidrome triad": decreased level of consciousness, pinpoint pupils and respiratory depression. Other symptoms include seizures and muscle spasms. Sometimes an opiate overdose can lead to such a decreased level of consciousness such that the person will not wake up.

  4. Opiate - Wikipedia

    en.wikipedia.org/wiki/Opiate

    Opiates with opioid activity are mainly used for pain management with the premise that there will be benefits for both pain & function that will outweigh the risks to the patient. [25] Another indication is symptomatic relief of shortage of breath, both in the acute setting (for example, pulmonary edema) and in terminally ill patients. [26] [27]

  5. Do you know the signs of an opioid overdose? Here’s how to ...

    www.aol.com/know-signs-opioid-overdose-help...

    Opioids depress the body’s ability to breathe, so an overdose can look like a lot of things, according to Cindy Hollinsworth, Communicable Disease and Epidemiology Manager with Whatcom County ...

  6. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    Opioids do not cause any specific organ toxicity, unlike many other drugs, such as aspirin and paracetamol. They are not associated with upper gastrointestinal bleeding and kidney toxicity. [71] Prescription of opioids for acute low back pain and management of osteoarthritis seem to have long-term adverse effects [72] [73]

  7. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    Substance use disorder (SUD) is the persistent use of drugs despite substantial harm and adverse consequences to self and others. [8] Related terms include substance use problems [9] and problematic drug or alcohol use.

  8. Narcotic - Wikipedia

    en.wikipedia.org/wiki/Narcotic

    Endogenous opioids (enkephalins, dynorphin, endorphin) do not bind specifically to any particular opioid receptor. Receptor binding of the opioid causes a cascade leading to the channel opening and hyperpolarization of the neuron. The opioid receptors have the following channel types: mu, K + channel; l delta, K + channel; kappa, Ca 2+ channel ...

  9. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    The opioid epidemic took hold in the U.S. in the 1990s. Percocet, OxyContin and Opana became commonplace wherever chronic pain met a chronic lack of access to quality health care, especially in Appalachia. The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history.